Self-emulsifying drug delivery systems and the application in drugs and cosmetics

Self-emulsifying drug delivery systems (SEDDS) have the potential to enhance bioavailability and therapeutic impact of active ingredients that are poorly water-soluble, low pemeability unstable. The ingredient, oil, surfactant, co-surfactant and/or co-solvent main elements SEDDS. Supersaturable SEDDS been developed increase efficiency ingredient loading by incorporating precipitation inhibitors (PIs) into help maintain supersaturated state, preventing in gastrointestinal tract. Due these benefits, studied applied drugs cosmetics various dosage forms including solidification (S-SEDDS) different techniques create powder, granules, pellets apply tablets, hard capsules as well soft capsules, lotions, some other semi-solid forms... This review mainly focuses on components, formulation, applications pharmaceutical cosmetic products.